Publicly available COVID-19 AIRR-seq data sets

The eight COVID-19 AIRR-seq data set from Kim, S. et al. “Stereotypic Neutralizing VH Clonotypes Against SARS-CoV-2 RBD in COVID-19 Patients and the Healthy Population” (DOI) is now available on the iReceptor Gateway!

We are almost at double digits! The ninth COVID-19 AIRR-seq data set from Kuri-Cervantes.et al. “Comprehensive mapping of immune perturbations associated with severe COVID-19” (DOI) is now available on the iReceptor Gateway!

Tenth COVID-19 study available in the AIRR Data Commons and through the iReceptor Gateway, and its a big one! 542M annotated sequences from the Adaptive Biotechnologies ImmuneRace TCR data (see Nolan et al. A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2) is now available for searching and comparison to the other COVID-19 studies in the AIRR Data Commons!

Twelfth COVID-19 study available in the AIRR Data Commons and through the iReceptor Gateway. 125K annotated sequences from Wen et al. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing) is now available for searching and comparison to COVID-19 and other studies in the AIRR Data Commons!

Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients
https://www.biorxiv.org/content/10.1101/2020.12.28.424622v1
Statement: The data that support the findings of this study have been deposited into CNGB Sequence Archive (CNSA: CNGB Sequence Archive (CNSA)) of CNGBdb with accession number 465CNP0001106.

Hmm, seems like we have fallen behind on making announcements here (although the updates were done on the main page). There are two new COVID-19 data sets available in the AIRR Data Commons and through the iReceptor Gateway . Sorry these were added some time ago (February and April respectively).

  1. Mor et al. Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors. PLOS Pathogens, Feb 11, 2021. DOI.
  2. Sokal et al. Maturation and persistence of the anti-SARS-CoV-2 memory B cell response. Cell, Volume 184, Issue 5, P1201-1213.E14, March 04, 2021. DOI.

The 15th COVID-19 AIRR-seq data set - and first vaccine study - from Goel, R. et al. “Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals following mRNA vaccination” (DOI) is now available on the iReceptor Gateway !