List of software for creating simulated data sets


A list of software developed to create simulated repertoires, either ab initio or using an existing repertoire as a base. See also which contains some additional details and was the base from which this list was created.

This is a wiki page. Please edit and add software you know about. However, note that this is not the place for closed-source commercial software vendors to advertise their products.

Tools that can be trained to mimic features of a given repertoire

Other related tools:

Tools that simulate mutations in an existing sequence or repertoire:

  • SHazaM (Gupta et al., 2017) - introduces mutations into sequences or lineage trees, according to an SHM mutability/targeting model.

B-T.CR Wiki Home

Don’t forget SHMulate. Introduces mutations into sequences (shmulateSeq) or lineage trees (shmulateTree) according to a SHM mutability/targeting model, such as S5F. Implemented as part of the SHazaM package in the Immcantation suite. Method reported in (Gupta et al., 2017).


Thanks Steve. I felt that it was best to introduce a third category for this and other related software. Feel free to edit or recategorise if you wish.