PhD position in Bioinformatics: Impact of HIV on B cells and its role in the genesis of B cell lymphomas

Universität Duisburg-Essen
We are one of the youngest universities in Germany and think in terms of possibilities, not limitations. In the heart of the Ruhr region, we develop ideas for the future at our 11 faculties. We are strong in research and teaching, live diversity, support potential, and are committed to real educational equality.

Activities and responsibilities
The University Duisburg-Essen (Campus Essen) offers a position (starting 2021-01-01 for three years) at the Faculty of Biology, Research Group Bioinformatics and Computational Biophysics (https://www.uni-due.de/zmb/bioinformatics-computational-biophysics/) as:

PhD student
(65% part-time, salary equivalent TV-L 13)

The successful applicant will work in a collaborative project aiming at the discovery of mechanisms that lead to high prevalence of B cell lymphoma in HIV infected. The project is funded by the German José Carreras Leukemia Foundation.

The focus will be on computational analyses of data from high-throughput experiments, specifically:

  • B cell receptor repertoire analyses
  • Whole genome analyses
  • Affinity assays
    For these analyses the PhD student will develop/apply computational methods.

The PhD student will participate in the BIOME graduate school.

Qualification profile
At least 8 semesters of successful studies with a Master in Bioinformatics, Biostatistics, Computational Biology, Biology or similar.

  • solid background in bioinformatics (sequence analysis, machine learning, etc.) and statistics (preferentially probabilistic modeling and Bayes inference)
  • Familiarity with processing and analysis of HTseq data
  • Very good programming skills, including R and python
  • Background knowledge in molecular and immuno-biology
  • Good communication skills (incl. ability of writing and speaking scientific english) and team working abilities

Benefits

  • Being part of a cutting edge research project
  • Interesting job in an excellent team
  • Supplementary training opportunities
  • Sports and health offers (university sports)

Send application until November 10, 2020 by e-mail to
daniel.hoffmann@uni-due.de
Prof. Daniel Hoffmann
Bioinformatics and Computational Biophysics
Faculty of Biology
University of Duisburg-Essen