Post-doctoral position - Oxford Vaccine Group, University of Oxford - BCR-repertoire / vaccines


The University of Oxford, Department of Paediatrics is seeking to appoint a suitably qualified Postdoctoral Research Assistant at the Oxford Vaccine Group (OVG), based at the Centre of Clinical Vaccinology and Tropical Medicine (CCVTM).

We are seeking a highly-motivated individual to join a multidisciplinary research group focused on applying systems immunology approaches to molecular data from clinical trials of vaccines to drive the development of the next generation of vaccines. A specific aim of this post is the development of B-cell receptor (BCR) repertoire sequencing methods to study vaccine induced immunity, and working with collaborators in the Target Discovery Institute (TDI) to combine BCR repertoire data with antibody sequencing data from mass-spectrometry to facilitate the identification of antigen-specific antibody sequences. Previous proteomics experience, whilst desirable, is not essential as support will be available through TDI to develop proteomic laboratory and analysis skills. The post will also involve the development and oversight within OVG of immunological assays applied to a variety of clinical trials samples together with communicating and working with a team of multidisciplinary scientists (including internal and external collaborators) to carry out systems vaccinology studies.

You will have a relevant PhD and possess experience and a good knowledge of both immunological techniques and high-throughput sequencing technologies. You will have a working knowledge of statistics and command line data analysis. You will be self-driven, highly motivated and have excellent organisational and interpersonal skills as the post involves collaboration within several groups and consortia.